International Journal of Academic Engineering Research (IJAER)   Year: 2018 | Volume: 2 | Issue: 10 | Page No.: 8-11 Bioethanol Production Process from Palm Rachis Using the Computer-Assisted Intrinsic Safety Index Method Mar?a José Sanjuan –Acosta, Karolayn Tobon- Manjarres, Samir Meramo –Hurtado, Karina A. Ojeda –Delgado, ?ngel D. Gonz?lez –Delgado Abstract: This article evaluates the safety of the process of obtaining bioethanol from the African palm rachis; the process studied has a capacity of 10,000 kg/h of raw material and is designed implementing the route of saccharification and simultaneous co-fermentation (SSCF). This analysis was carried out through the methodology INHERENT SAFETY INDEX OF PROCESSES (ISI), which seeks to minimize the hazards of chemical processes from its conceptual design, evaluating two intrinsic variables of all processes: chemical and operational. The first one related to the chemical properties and dangerousness of the substances that intervene in the process such as reaction heats, flammability, toxicity, explosiveness, corrosiveness and the second one related to the operation variables of the process such as temperatures, pressures and equipment that conform the process. By means of this evaluation, an ISI of 23 points was obtained, with a chemical index of 18 and a process safety index of 5. Compared to the literature, this process had a good safety performance, however, it is important to pay special attention to by-products that can be generated from secondary reactions.