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| Correlation between Toxocariasis and Complement(C3and C4) in Asthmatic and Epileptic Patients |
Ban Anas Sabbar, Nadham Kadham Mahdi, Assim Khalid Assim
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Abstract:
Objective: To study effect of Toxocara infection on level of complement proteins(C3 and C4) in serum of asthmatic and epileptic patients .
Subjects and Methods: 60 asthmatic patients(30 seropositive for Toxocara antibody and 30 seronegative) and 32 epileptic patients(16 seropositive for Toxocara antibody and 16 seronegative) in addition to 30 healthy individuals as a control were enrolled in this work which carried out at Basra Teaching Hospital in Iraq from Dec 2017 to Nov 2018 . C3 and C4 concentration were assessed by immunoturbidometric assay by using the Abbott Architect c System.
Results: The results were referred to elevation of C3 concentrations in seronegative and seropositive groups of either asthmatic or epileptic patients when they compared with control group with significant difference between patients and control group(p=0.0001) .Concerning C4,it?s concentration level was convergent in patients groups (seropositive &seronegative ) and control group for asthmatic or epileptic patients except seronegative asthmatic patients which had elevation level of C4 concentration in comparison to other groups. statistical analysis revealed no significant difference between all these tested groups.
Conclusion:It was difficult to determine the role of complements (C3 andC4) in toxocariasis of asthmatic or epileptic patients and it needs further studies.
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