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| Anthelmintics Efficacy of Albendazole, Levamisole and Ivermectin Against Gastrointestinal Nematodes (GINs) Infection in Goats in Nyala Area, South Darfur State, Sudan |
Salma A. Hassan, Abbakar A. Mohammed and Fayza A.Omer
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Abstract:
The lack or reduced efficacy of some anthelmintics to control the gastrointestinal nematodes of goats was recognized as one of the greatest threats to grazing livestock production. The objective of this study was to investigate whether the perceived change of anthelmintics efficacy in goats in South Darfur State is due to treatment failure because of under-dosing or the actual development of anthelmintics resistance. Experimental treatment trials were conducted on naturally infected goats in three randomly selected goats, farms to evaluate the efficacy of three types of commonly used anthelmintic drugs; Albendazole (ABZ), Levamisole (LVE) and Ivermectin (IVM) using faecal egg count reduction test (FECRT). The efficacy of ABZ was (89%) and (97.4%), while it was (85%) and (95.7%) for LVE, in the first and second farms respectively. IVM showed high efficacy (98%) in the third farm. Mean faecal egg counts were calculated on days (0), (7), (14) and (21). ABZ and LVE showed lowest egg count (30±21.34) and (50±30.73) on day (7) respectively, while IVM showed the lowest count (15.38±10.42) on day (14). Species composition of nematodes was determined by identification of larvae recovered from faecal cultures. The study concluded that Haemonchus contortus was observed to be resistant to all three types of anthelmintic drugs. Further studies using molecular or other robust techniques are recommended to evaluate the efficacy of these drugs in the area.
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