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| Antibacterial Activity of Ethanol and Aqueous Extracts of Moringa Oleifera Lam. against Some Human Pathogenic Bacteria (In Vitro Study) |
Omer Abu Elhasan, Omer M. Abd Elbagi, Hind O. Taha, Abuagla M. Dafalla
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Abstract:
Medical plants are considered one of the most important sources of food and treatment worldwide and especially in Sudan. Sudanese were using medical and aromatic plants - including Moringa - for the treatment of many diseases. On the other hand, scientists and health care providers are facing the continuous problem of bacterial antibiotic resistance, which has become a great challenge in eradication of infectious diseases. This study was conducted in Wad Medani College of medical sciences and technology (MST) in the period from Augusts to November 2014, to evaluate the antibacterial activity of Moringa oleifera leaves extract against Gram positive and Gram negative bacteria. The organisms under study include: staphylococcus aureus, streptococcus pyogen, Salmonella typhii, Escherichia coli and pseudomonas aeroginosa. Extraction of active substances from moringa leaves was done by using two extraction methods, aqueous extract and ethanol extract. The antimicrobial susceptibility tests were performed according to the standard procedures. The results of this study revealed that the aqueous moringa extract mean zone of inhibition was 29 mm for staphylococcus aureus, 25 mm for streptococcus pyogen, 30 mm for pseudomonas aeroginosa. 22 mm for Escherichia coli and 32 mm for Salmonella typhii, And the Ethanolic moringa extract mean zone of inhibition was 31 mm, 30 mm, 29 mm, 25 mm and 31 mm for the previous bacteria respectively. This study verifies that Moringa oleifera leaves extract has an (in vitro) antibacterial activity against the organisms under studding. Clinical trials (in-vivo) are needed to test the activity of Moringa oleifera against bacterial infections.
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