Abstract:
This study aimed to associate between Sudanese serum total IgE and S. mansoni infection. A cross sectional study was conducted in the period between March-October 2011. The study was conducted on 764 serum samples (110 were positive for S. mansoni and 654 were negative for S. mansoni) and 4 serum samples as European control were examined. The age ranged between 4-85 years, mean age was 23 years old. Faeces samples were collected from all the subjects included in the study and examined by using Kato-Katz technique. Also, serum samples were taken from all subjects and examined by using Human IgE Ready-SET-Go! ELISA (eBioscience, Frankfurt, Germany) technique was used. The results showed that there was a statistically significant relationship between the mean of total IgE and S. mansoni infection (p=0.000). The results demonstrated that the relationship between the mean of total IgE and age-groups was fluctuated. The results reflected that there was a statistically significant relationship between the mean of total IgE and the gender (p=0.000). In addition to, there was a statistically significant relationship between the mean of total IgE and treatment (p=0.000). The results revealed that the relationship between the mean of total IgE and intensity of S. mansoni infection was fluctuated while there was a statistically significant relationship between the mean of total IgE and Kato technique (p=0.000).
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