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| Probiotic Microorganisms in Diet and Their Effect on Inflammatory Bowel Disease (Ulcerative Colitis) |
Milad Daneshniya , Masome Behrouzian , Mohammad Hossein Maleki , Mohammad Reza Hassanjani
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Abstract:
A group of inflammatory diseases that affect the colon and small intestine are called inflammatory bowel diseases (IBD), and Ulcerative colitis (UC) and Crohn's disease (CD) are two common types. These diseases increase the risk of colon cancer, inflammation of the joints, eyes, and skin and increase the risk of a blood clot in the arteries.Researches have indicated that a variety of factors, such as diet, genetics, intestinal flora, etc., are effective in getting infected by the mentioned disease, which affects the large intestine. Conventional synthetic drugs for reducing the inflammation and also for the treatment of this disease have serious and more side effects for the consumer, causing researchers to seek alternative treatment methods with fewer side effects. Studies have demonstrated that probiotic microorganisms can exhibit anti-inflammatory properties through various mechanisms. The present review showed that the major mechanism of probiotics for coping with inflammatory bowel disease is related to the consolidation of the epithelial barrier and the production and secretion of interleukins.
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