Abstract:
This cross-sectional study was conducted in New Halfa City-Eastern Sudan to evaluate serum interleukin (IL)-5 and their associated level factors in Sudanese patients infected with human Schistosomiasis mansoni during the period from March to June 2011. The study was conducted on 55 subjects (33 were positive for S. mansoni and 22 were negative for S. mansoni). The age ranged between 4-60 years old, and the age was divided into 4 groups 4-12, 13-19, 20-45 and 46-60 years old. Faeces samples were collected from all the subjects included in the study and examined by using Kato-Katz technique. Also, serum samples were taken from all subjects and examined by using Human IL-5 Immunoassay (R&D Systems) technique. The results showed that the results of IL-5 were ranged from 0.00-52.84 pg/ml; the mean was 3.12 pg/ml. The results reflected that the relation between the mean of IL-5 and the gender was significant (p=0.000). The results demonstrated that the relationships between the mean of IL-5 results and age-groups, treatment of S.mansoni infection, Kato-Katz technique, intensity of S. mansoni infection and tribes were insignificant. The results revealed that the mean of serum IL-5 in S. mansoni infection illustrated positive correlation with gender, treatment, Kato technique, intensity of infection, tribes and age groups.
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