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| Probiotic Microorganisms in Diet and Their Effect on Crohn's Disease |
Mohammad Hossein Maleki, Milad Daneshniya, Masome Behrouzian, Mohammad Reza Hassanjani
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Abstract:
Ulcerative colitis (UC) and Crohn's disease (CD) are common types of inflammatory bowel diseases (IBD). Investigations have revealed that some neurological factors, intestinal flora, etc., are effective in getting infected by the Crohn's disease, which affects various parts of the gastrointestinal tract. Standard treatment methods for Crohn's disease are based on the alteration of the immune system with corticosteroids, immunosuppressants, and surgery, along with using synthetic drugs. The side effects of each of these methods, along with the awareness of the role of enteric bacteria in the development of Crohn's disease have attracted researchers' attention toward the probiotics as an effective factor in the treatment of this disease. Probiotics can be used as a part of the food or as probiotic supplements and enter the body. Due to some uncertainties in the production and measurement of probiotic supplements, it is recommended that food products containing probiotics to be used as the main source of these microorganisms. However, in case of emergency and treatment of inflammatory bowel diseases, probiotic supplements are recommended along with probiotic foods.
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