International Journal of Engineering and Information Systems (IJEAIS)   Year: 2020 | Volume: 4 | Issue: 6 | Page No.: 24-41 1Factors that Determine the Sustainability of Microfinance Institutions in Ghana Dr. Ramatu Ussif, Associate. Prof. Dr. Murat Ertugrul, Prof. Dr. Metin Coskun, Associate. Prof. Dr. Ismail Onur Baycan Abstract: Microfinance performs a key role in Ghana and sub-Saharan African countries in their development. Ghana has witnessed unprecedented collapses and unsustainability of microfinance institutions in recent years (2017-2019) necessitating such studies to unravel the determining factors using selected microfinance institutions in the country. The article also investigates the reason for the revocation of microfinance licenses, besides reasons for microfinance collapse and their remedies. Data was gathered and analyzed using SPSS and Microsoft Excel. The results reveal that the factors affecting microfinance institutions' sustainability are positively and significantly driven by minimum capital requirement, credit default, outreach-levels, government policies, high-profit-motive, and capital structure. Insufficient training, poor management, insufficient monitoring/supervision, the collapse of other institutions, and panic withdrawals are the reasons why most microfinance institutions collapsed. Finally, we recommend that there should be compulsory training/capacity building, outreach programs, low-interest-rates, and experienced-staff to strengthen the organizations' performance and maintain sustainability.