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| Plasma Lipid Profile in Type 2 Diabetic Patients with Retinopathy in Khartoum State |
Nuha Eljaili Abubaker ? , Hind Mohamed Ahmed, Seif eldeen Ahmed Mohamed and, Ahmed Bakheet Abd
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Abstract:
Background: Diabetic retinopathy (DR) is a very common complication of diabetes mellitus, leading to visual deficits and blindness around the world. Aim: Across-sectional study conducted to measure serum lipid profile in type 2 diabetic patients with retinopathy. Methodology: Fifty samples were collected from type 2 diabetic patients with retinopathy in period between July to November 2019, chosen randomly from Alfaisal eye center, and 25 type 2 diabetic patients without retinopathy as control. Sherwood colorimeter 260 was used for measurement lipid profile (total cholesterol, triglycerides, LDL-c and HDL-c) and results were analyzed using statistical of package social science (SPSS) computer program. Results: This study found that, in diabetic patients with retinopathy total cholesterol and LDL-c were significantly increased when compared to a control group (mean + SD: 174.5+ 36.8 mg/dl versus 146.62+ 7.0mg/dl p. value = 0.00), (mean+ SD: 105.6+ 33.8 mg/dl versus 81.2+ 21.5 mg/dl p. value = 0.00) respectively. There were insignificant difference for HDL-C and triglycerides compared with control group (mean + SD: 36.4 +8.4mg/dl versus 33.6+ 5.7 mg/dl, p. value =0.146), (mean+ SD: 120.8+ 61.3 mg/dl versus96.4+ 38.4mg/dl, p. value =0.074) respectively. The result showed, there were no correlation between Cholesterol, Triglycerides, LDL-C and duration of the disease (r=0.058, p-value=0.622), (r=-0.010, p-value=0.933), (r=0.045, p-value=0.703) respectively, and there was significant weak negative correlation between HDL- C level and duration of disease (r=-0.235, p-value=0.043). Also there were no correlations between cholesterol, triglycerides, LDL-C and age of diabetic retinopathy (r=0.077, p-value=0.514), (r=0.035, p-value=0.768), (r=0.081, p-value=0.489) respectively and there was significant weak negative correlation between HDL-C level and age of diabetic patients with retinopathy (r=-0.255, p-value=0.027).
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