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| Comparison of Shear-Wave Elastography and Biopsy in the Evaluation of Liver Masses |
Abdalmalek Ismail, Dr. Raham Bacha, Dr. Waqas Ahmad, Dr. Mohammad Atif, Dr. Ahmad Idris , Syed Muhammad Yousaf Farooq, Asif Hanif:
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Abstract:
Background: Liver cancer is the 6th most occurrence disease around the world with a rating of 749,700 in the year 2008. The maximum number of liver cancers 75-90 % among the people were diagnosed with hepatocellular carcinomas (HCC) where HCC is a malignant tumor effect the liver parenchymal cell. Share waves elastography (SWE) is a technique used for the evaluation of liver masses in all aspects however SWE showed high sensitivity, specificity and predictivity of masses. Whereas the liver biopsy is still considered to be the gold standard. Objective: To compare Biopsy and shear-wave elastography findings in the differentiation of liver masses. Methodology: The study was cross-Sectional. 133 patients were included in the study, 84 patients (mean age:42.9762 years; all females) underwent SWE and 40 (mean age:42.8750 years; male:14 and female:26) patients underwent both technique SWE and biopsy. The study was conducted at Shaukat Khanum Memorial cancer hospital & Research center and General hospital. The duration of the study was 9 months. The sampling Technique was Convenient sampling. All the individuals having liver fibrosis were included while Liver transplant patients were excluded. Toshiba i-800 US machine (Shear Wave Elastography software) was used in the study and hospital protocols were followed. Data were analyzed by SPSS version 23. Results: out of 84 participants who underwent SWE, 50 participants showed masses and 34 had negative results. participants who underwent both SWE and biopsy (no:40) showed masses in 27 participants when they underwent SWE and 33 after diagnosis of biopsy. Sensitivity, specificity, positive predictive value and negative predictive value of shear wave elastography were 100 %, 53.85%, 81.82%, 100% respectively. Conclusion: Shear wave elastography was found to have magnificent diagnostic achievement in assessing liver fibrosis with liver disease. The SWE has got high sensitivity but not specificity. However, liver biopsy is still considered to be the gold standard.
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