International Journal of Academic Health and Medical Research (IJAHMR)   Year: 2021 | Volume: 5 | Issue: 10 | Page No.: 1-5 Meckel Gruber syndrome, A case report (3 cases) Mohamed Saleh Abderrahmane, RAHMOUNE Mohammed, Chaara Hekmat, Jayi Sofia, Fdili Alaoui Fatima Zahra, Melhouf My Abdellilah Abstract: : Meckel Gruber syndrome is a rare autosomal recessive poly malformative syndrome defined by occipital encephalocele, polydactyly and cystic renal dysplasia. Ultrasound is currently the best tool for antenatal screening of this lethal poly malformation and its confirmation is done by karyotype study. We report three cases of Meckel syndrome discovered by ultrasound.