International Journal of Academic Health and Medical Research (IJAHMR)   Year: 2021 | Volume: 5 | Issue: 10 | Page No.: 35-36 Vulvar Leiomyosarcome Rare Pathology: A Case Report and Review of the Literature Dr Mohamed Saleh Abderrahmane, Dr Rahmoune Mohammed, Pr Fdili Alaoui Fatima Zahra , Pr Jayi Sofia, Pr Chaara Hekmat, Pr Melhouf My Abdellilah Abstract: Leiomyosarcoma of the vulva is a rare malignant tumour with smooth muscle differentiation, occurring in the 4th or 5th decade. Its malignancy is difficult to assess. The rarity of the disease is a challenge for prognostic classification. We report the case of a 49 years old patient, followed and operated in the University Hospital Center HASSAN 2 of Fez Morocco.