Abstract:
The discovery of antibiotics is an important turning point in humanity's fight against diseases throughout history. However, the rapidly increasing world population and the increase in the use of antibiotics cause the emergence of antimicrobial resistance among bacterial agents and more biofilm structure in bacteria. Humanity is facing an antibiotic crisis due to the increasing number of people with bacterial biofilm-related infectious diseases. The formation of a biofilm structure that inhibits the effect of antibiotics is associated with the ability of pathogenic bacteria to make them sick. Bacteria with biofilm structures are 1000 times more resistant to antibiotics and disinfectants than bacteria with planktonic structures. In this situation that humanity is facing today, it is of great importance to discover agents with antibiofilm effects. In this study, antibiofilm activities of Sideritis trojona against Bacillus subtilis DSMZ 1971, Escherichia coli ATCC 25922, Listeria monocytogenes ATCC 7644, Listeria innocua, Escherichia coli 1214816 strains were determined. The test study determined that the plant extract had a positive antibiofilm relationship to Listeria monocytogenes strain and a negative antibiofilm relationship to Escherichia coli 1214329 strain.
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