International Journal of Academic Health and Medical Research (IJAHMR)   Year: 2021 | Volume: 5 | Issue: 2 | Page No.: 55-61 Human Toxocariasis among Asthmatic Patients in Basrah Province/ Iraq Ban Anas Sabbar, Assim Khalid Assim, Nadham Kadham Mahdi Abstract: Objective: To study seroprevalence of Toxocara antibody immunoglobulin G , epidemiological risk factors and assess the immunological pattern including cytokines interleukin-6 and interleukin-10 and immunoglobulin E among bronchial asthmatic patients in Basra. Subjects and Methods: 113 asthmatic patients with ages range from 2-80 years (51 females and 62 males) and 109 apparently healthy persons(control) (59 females and 50 males ) were enrolled in the study. It was done during the period from December 2017 to November 2018 at Pediatric and Respiratory Consulting Clinic of Basrah Teaching Hospital. The risk and epidemiologic factors were assessed by a questionnaire which was completed by the patients themselves or relative. immunoglobulin and cytokines were assessed by using ELISA while IgE by immunoturbidometric assay for every asthmatic patients and healthy group. Results: Thirty (26.55%) asthmatic patients were seropositive for Toxocara antibody (IgG) in comparation with 2 (1.83%) of control with significant difference between them (p=0.0001). There wasn't significant difference between seropositive and seronegative asthmatic patients in regard to characteristic features of population and risk factors . The immunological assessments revealed an elevation in the level of IgE and IL-10 in seropositive group as compared with Seronegative while IL-6 concentration was elevated in seronegative group. Conclusion: Toxocariasis may play role as a risk factor for asthma. Thumb sucking and family history may increase risk of infection. Toxocariasis may lead to elevated levels of IgE and IL-10 in these patients but it appears has weak influence on concentration of IL-6.