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| Cytomorphological Pattern of Urine among Sudanese Patients with Urinary Tract Stone in Shendi Locality |
Mohammed Abdelgader Elsheikh Mohammed, Ph.D, Mahmoud Ibrahim Osman Hamad, M.Sc , Alkhair Abd Almahmoud Idris, Ph.D , Rayan Jaffer Mohammed Khalfalla, B.Sc , Samia Abduelaziz Hassan Bashir, B.Sc , Adan Tagaldeen Ahmed Almsaadd ,B.Sc, TasneemMutasimYousifF
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Abstract:
Background: Urinary calculi can induce urothelial cellular abnormalities comparable with those of malignancy. Aim: To detect the Cytomorphological Pattern of Urine in Patients with Urinary Tract Stone among Sudanese patients in Shendi Locality. Materials and methods: This was descriptive cross-sectional study conducted in Shendi locality -River Nile State-Sudan, samples were collected from different blocks. Then the collected samples were transferred to Histopathology lab where they processed and stained. A questionnaire for collection demographic data was performed with every participant. Results: The cytological changes in voided urines were analysed from cases and controls, 35 urine samples were taken from each group. Cytological changes were detected in (25/35) 71.4% among cases, and (0/35) 0.00% in controls. No malignancy was seen in all samples. Dyskaryosis in urine cytology revealed that, (12/35) 34.2% of cases with dyskaryosis, while no sample of controls contain dyskaryosis. Cellular atypia was detected in (19/35) 54.2% in the cases and 0/35 0.00% in controls. Metaplasia was detected in (19/35) 54.2% in cases and 0/35 (0.00%) in controls. Features of urinary tract infection were detected in (17/35) 48.5 % in cases and (3/35) 8.57% in controls. Chronic Inflammation conditions were detected in (14/35) 40% of case, (1/35) 2.85% of controls, while acute inflammation present in (8/35) 22.8% of cases and (1/35)2.85%.of controls.Conclusion: Urinary tract stone are more common in peoples live in Shendi town than people's lives in surrounding areas and Metaplasia is the most common cytological changes.
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