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| Nikel Nanoparticle with Sunflower Plant Leaf Extract and Antimicrobial Potential against Clinical Bacterial Isolates
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Owolabi, Oluwafemi Akinkunmi, Lawal, Ibraheem Kehinde, Abideen, A. Adekanmi, Ayoade, Julius Oluwatosin, Oluwagbemiga, Micheal Ajewole, Awodiran, Tunji Paul
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Abstract:
Despite antimicrobial drugs' widespread efficacy against diseases, a major source of concern is that certain bacteria have acquired resistance to them as a result of their overuse. The current study focuses on the manufacture of nanoparticles from sunflower leaf extract and the evaluation of their potency against bacteria from a clinical source. Sunflower leaves were collected in open spaces in Akoda, Osun State, Nigeria. Using a conventional approach, a nickel nanoparticle was produced from a sunflower plant extract. Standard UV-visible spectroscopy techniques were used to characterize the nanoparticle. Using agar well diffusion methods, the antibacterial properties of nickel nanoparticles and sunflower leaf extract were investigated against E. coli and Proteus sp. According to the results of their characterization, the spectra of produced nanoparticles can be detected as two distinct peaks. The first peak, at 245 nm, relates to the formation of nickel nanoparticles, whereas the second peak, at 675 nm, corresponds to the formation of nickel nanoparticles. Leaves extract (sunflower) and manufactured nickel nanoparticles inhibited E. coli in zones of 5 mm and 2 mm, respectively. Leaf extract (sunflower) and manufactured nickel nanoparticles had no zone of inhibition against Proteus sp. Nickel nanoparticles made from plants were found to have antibacterial action against E. coli. They were cheap, eco-friendly, and cost-effective. As a result, the nickel nanoparticles that have been manufactured have been proven to be effective against clinical isolates.
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