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| The effect of Anti Retrovirus Therapy regimens on viral load and Hemoglobin in Sudanese patients whom suffered from HIV/AIDS
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Mohammed I. Mursal, Hani M. Abdalla, Abuagla M. Dafalla, Yousif A. Mohammed, Abdelrhman E, Abaker
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Abstract:
Introduction: Before people start antiretroviral therapy (ART), health-care providers should initiate a detailed discussion about the willingness and readiness of patients to initiate ART, the antiretroviral (ARV) drug regimen, dosage, scheduling, likely benefits, possible adverse effects, has historically been based on clinical indications, such as viral load and Hemoglobin estimation the required follow-up and monitoring visits. Objective: The aims of this study to evaluate the effect of Anti Retrovirus Therapy regimens on viral load and Hemoglobin in Sudanese patients who suffered from HIV/AIDS. Materials and Methods: A cross-sectional center-based study conducted in 100 patients of ART Center in Medani Teaching Hospital, Statistical analysis was performed using SPSS statistical software trial version 22. The P. Value< 0.05 was considered as statistically significant. Result: About 100 HIV patients were included in this study; HIV positive under treated, were assessed in ART center in Medani Teaching Hospital, with males accounting for about (44%) and females accounting for about (56%), Patients ranged categorized into four hemoglobin estimation group; 44 normal from (13.2g/dl - 16.6g/dl) for male and (11.6g/dl - 15g/dl) for female; 43 mild (10g/dl to levels within normal limit); 9 moderate (8.0 - 10g/dl); 4 sever. Analysis of viral load count in the present study the test accounts the viral load before and after initiating the ART 100, There were decrement in viral load after treatment in this study (P-value = 0.000 highly significant), The rate at which this happens can vary a lot between individuals. In some people, it can take months or even years for their viral load count to climb towards normal levels for people of their age. The mean value viral load count before ART was 34431.58 and after initiating the ART, the mean value of viral load count decreased to 811.35. Conclusion: In this study there's very good evidence that the HIV treatment available today will work against the virus in the long term and keep the viral load undetectable indefinitely, the treatment not working is likely to mean that viral load and hemoglobin will increase and your CD4 cell count, an important indicator of the health of immune system, will fall. This situation increases your chances of becoming ill because of HIV. There is significant effect of Anti Retrovirus Therapy on viral load and Hemoglobin. These findings may be helpful to HIV-positive individuals and their attending physicians in understanding disease progression.
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