Abstract:
Krukenberg tumors are defined as very rare ovarian metastases whose etiopathogenesis is still poorly understood. Most often of digestive origin, in particular gastric and colonic, and more rarely from an extra-digestive starting point, such as the breast and the thyroid. They represent 1 to 2% of ovarian tumors in women, with an average age of diagnosis of 45 years. Our study is a retrospective descriptive analysis, spread over a period of 10 years from January 1, 2010 to December 31, 2020, involving 16 cases of patients with Krukenberg tumors collected in the obstetrics gynecology department II, at the University Hospital Center (CHU) Hassan II of Fez. The aim of our study was to improve our knowledge of Krukenberg Tumors, to describe the epidemiological profile, to study the clinical and paraclinical particularities of these tumours, to underline the different therapeutic strategies, to evaluate the prognosis of this pathology, and finally to compare the results of our series with data from the literature. In total, 16 cases of Krukenberg Tumors were included in our series, the average age in our patients was 46.2 years with extremes ranging from 26 years to 76 years. Almost half of the patients were still in the period of genital activity (43%) and multiparous (62.5%). Abdominal distension (46%) followed by pelvic pain (38%) were the most frequent clinical signs. Ultrasound was performed in 81.25% of our patients, it confirmed the existence of a pelvic mass in 100% of cases. CT was performed in 43% of cases. The current treatment of Krukenberg tumor is essentially surgical, consisting in the earliest possible extraction of the primary tumour, followed by a radical treatment of the ovarian tumour. The contribution of complementary treatments is debatable; however, adjuvant chemotherapy retains positive efficacy. In general, the prognosis for this category of tumor remains poor, with a median survival of 12 months.
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