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| The Detection of Nasopharyngeal Cytological smears Among Positive COVID-19 Test Patients in Omdurman Medical Military Hospital (Sudan).
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Mujahed Nooraldaem Mirghani Adam, Ph.D , Ismail Osman Khalid,MD , Ali Seedahmed Mohamed Ali, Ph.D , Nadia Madani Mohamad, Ph.D , Alkhair Abd Almahmoud Idris, Ph.D .
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Abstract:
Background: The role of the cytology laboratory in a patient with known COVID-19 is limited. Objectives: The study aimed to detect the nasopharyngeal cytological smears changes among positive COVID-19 test patients in Omdurman medical military hospital in Sudan. Materials and methods: This study was carried in Sudan.Nasopharyngeal and oropharyngeal cytological smears were adopted. The total number of samples were 150 samples. The nasopharyngeal and oropharyngeal swabs were centrifuged, smeared and parallel numbers fixed in 90% ethyl alcohol and other air dried fixed. Results: In terms of nasopharyngeal cytological smears, the microscopic examination of the nasopharyngeal smears did not reveal important cytological and pathological alterations. The observation of the nasopharyngeal smear also revealed an abnormally high number of lymphocytes (Lymphocytosis) and a lot of dry and wet mucous amount in different population which made shedding for a lot of inflammatory cells. Therefore, the cytopathic alterations were of little significance. A possible explanation could be the cytological nasopharyngeal patterns associated with nasal or throat scraping method not nasal swap which is a non-invasive method to take a sample of nasal mucosa. Each of the nasopharyngeal swabs did not reveal epithelial cells or glandular cells. A careful and thorough search failed to detect any viral inclusions and this due to the absence of squamous cells. This suggests that claims of viral inclusions with covid-19 disease may, rather, represent nonspecific cytopathic effect in nasopharyngeal swabs such as lymphocytosis. Conclusion: The smears were revealed a lot of dry and wet mucous amount in different population.
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