|
|
| |
| Impact of Covid 19 on the activity of Pharmaco-toxicology laboratory of the CHU Hasan II of Fez Morocco
Download PDF
|
MOURABITI Hajar, , , HOUMMANI Hasnae, , AMRANI HANCHI Sahar,, CHEBAIBI Mohamed, and ACHOUR Sanae,
|
Abstract:
Introduction. The pandemic associated to the SARS-Cov-2 coronavirus has presented the world with an unprecedented situation with impacts on different areas. The activities of CHU Hassan II in Fez were probably affected. In this work, we will assess the activity of the pharmacotoxicology laboratory during the Covid-19 period (2020) by comparing the results with those of the previous year (2019). Methods. It is a retrospective study that aims to compare the covid 19 period (between March 2020 and February 2021) with the previous year (between March 2019 and February 2020), and which concerns all intoxications and dosage of medicines received at the laboratory. Results. The number of requests for analyzes received during covid 19 period showed a decrease from 440 requests to 312 compared of the same period of the previous year. In addition, the requests for therapeutic drug monitoring has decreased. Indeed, 211 requests has been received in 2020 while in 2019, 329 requests were received .The dosage requests for depakinemia and carbamazepinemia fell respectively (190 and 52 in 2019 while in 2020, 127 and 12). On the other hand, the dosage of amikacinemia, research requests for pesticides and medicines remained stable, which is not the case for addictive drugs analysis, that shown a decrease; 209 requests in 2019 and 111 in 2020. Toxicological screening by HPLC-DAD was carried out in 2020 in 39 cases compared to 55 in 2019. Conclusion. The Covid-19 pandemic had repercussions on the physical and psychological health of the population, resulting in a change of the profile of requests for pharmaco toxicological analyzes during this period.
|
|
|
| | |