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| Uric acid level and Blood urea Nitrogen/Creatinine Ratio in Pre- eclamptic Ladies (Sudan)
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Maazza Omer Adam , Rehab Omer A. M. Gibla
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Abstract:
Pre-eclampsia is a pregnancy related syndrome; and one of the hypertensive disorders associated with different organ involvement, marked by new onset hypertension and protein-urea. This work was conducted as a cross sectional comparative study aiming to assess, uric acid level and blood urea nitrogen/creatinine ratio in pre-eclamptic women visiting Om-dorman maternity hospital from March to June 2022 . The samples were collected from (130) pregnant ladies, eighty (80) of them were diagnosed as pre-eclampsia cases and (50) were non-pre-eclamptic (control). Uric acid levels, urea and creatinine were measured. Blood urea nitrogen and urea nitrogen/creatinine ratio were calculated. The obtained results were statistically analyzed using (SPSS) program. Significant increase in uric acid level was shown among the pre-eclamptic (7.11±2.08 mg/dl) compared to the control group (3.65 ± 1.06 mg/dl) with p. value (0.000). On the other hand Blood urea nitrogen creatinine ratio showed insignificant increase in the pre-eclampsia group (14.92 ± 5.56), compared to that of control (12.91 ± 7.32) with p. value as (0.099). The levels of urea, creatinine and blood urea nitrogen were significantly increased in the pre-eclamptic cases than the control, with p. values (0.001, 0,022 and 0.001) respectively. No correlation was shown between age and pre-eclampsia phenomena.
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