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| Common bacterial isolates of wound infections and their antimicrobial susceptibility, Gezira National Center for Pediatric Surgery, Sudan
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Mohamed Tageldin , Omer Abu Elhasan, Hajir Mohammed Hussien, Sanaa Mohammed Yousif, Salma Omer Ibrahim Hadeel Omer Mirgani, Hind Elhaj Mohamed, Elhadi Abdalla Ahmed
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Abstract:
Background An increased antibiotic resistance of bacterial isolates from wound infections is a major therapeutic challenge. The aim of this study was to identify bacterial isolates associated with wound infection and to determine their current antimicrobial susceptibility profile. Methods: Descriptive cross-sectional study was followed, a total of 170 wound swabs were cultured aerobically at Gezira National Center for Pediatric Surgery, Wad Medani, Sudan in the period from December 2017 to march 2020. Swabs from different wound types were collected aseptically and analyzed using standard bacteriological procedures. Antimicrobial susceptibility testing was performed using disc diffusion technique as per the standard protocol. Demographic and bacteriological data were collected using a data extraction sheet. The data were cleaned, entered and analyzed using SPSS version 20. Results: Total positive bacterial growth revealed of 85.9% (146/170); of which 60% (102/170) were gram positive while 25.9% (44/170) were gram negative. Staphylococcus aureus was the predominant isolated organism 96 (56.5%), followed by Escherichia coli 34 (20%), Coaglase-negative staphylococci (CNS) 6 (3.5%), Klebsiella pneumoniae 6 (20%) and Pseudomonas aeruginosa 4 (2.4%). A 52.9% (90/170) of samples obtained from drainage surgical procedures, followed by 30% (51/170) incision, 11.1% (10/170) circumcision, 3.5% (6/170) appendectomy and 2.3% (4//170) laparotomy. Antimicrobial susceptibility for Staphylococcus aureus showed high level of drug resistance for methicillin with percentage of 96.9%, followed by cefotaxime 44.7% and cefixime 21.8%, while meropenine was the drug of choice with full sensitivity 100 % followed by vancomycin (90%), and gentamicin 86%. Conclusions: Staphylococcus aureus responsible for most cases of wound infections, and isolated gram negative rods were relatively more sensitive to selected antimicrobials.
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