International Journal of Academic Health and Medical Research (IJAHMR)   Year: 2023 | Volume: 7 | Issue: 7 | Page No.: 27-31 Liquid Based Cytology versus Conventional Pap for Evaluation of Cervical Smear among Reproductive Women, Wad Medani, Gezira State, Sudan, 2023 Download PDF Esraa Elshaikh Eltayeb Osman,Mohamed Siddig M.Elbashir, Rayan Sidig Adam Abdelgalil, Yasmin Elsamani Elwasila, Mohamed Elsanousi Mohamed, Elhadi Ibrahim Miskeen and Bakri Yousif M.Nour Abstract: Introduction: Cervical cancer is the second most common cancer among Sudanese women preceded by breast cancer. Cervical cytology "by its two branches conventional pap (CP) and Liquid Based Cytology (LBC)" is a stepping stone in cervical cancer prevention and cure. Aim: This study aimed to compare between two collection and preparation methods of cervical cytology, conventional Pap smear (CP) and manual LiquiPREPTM (LP), for evaluation of cervical smear among Sudanese reproductive Sudanese women. Methodology: The study included a total of 137 Sudanese reproductive women attended to Wad Medani Obstetrics and Gynecology Teaching Hospital and some private clinics during the period from February 2020 to January 2023. Both manual LP Smears and CP smears were prepared and evaluated according to The 2014 Bethesda System for Reporting Cervical Cytology. Result: From 137 CP and 137 LP, satisfactory smears were 134 and 136 respectively. LP improved background clarity (P = 0.001) and provided evenly distributed cellular pattern (P = 0.000). Pathogenic microorganisms were identified in 23 CP and in 22 LP smears. Cytomorphological findings were relatively similar in both CP and LP (P = 0.536). Conclusion: LP reduced U/S (unsatisfactory/satisfactory) rate, improved background clarity and provided evenly distributed cellular pattern over CP. Detection of microorganisms and cytological changes was relatively similar in both CP and LP.