International Journal of Academic Health and Medical Research (IJAHMR)   Year: 2023 | Volume: 7 | Issue: 9 | Page No.: 1-3 Antimicrobial Activities of Guiera Senegalensis Leaves Extract Download PDF Moawia Adam Mohammed , Mustafa Abakar Mustafa, Mudather Elnoor Younis Abstract: A deepening of understanding the plants extracts mechanisms and pathways of antimicrobial activities have been the basic requirements for the development of so called traditional medicine. Guiera senegalensis (family of combretaceae) leave used in various ways for medicinal purpose, in Sudan, Senegal, Gambia, Mali, Niger, Burkina Faso and Nigeria traditional healers use leave of G.senegalensis to treat several diseases . The present study aimed to determine antimicrobial activity of G.senegalensis leaves extract against six microbial isolates (Staphylococcus epidermidis, Staphylococcus epidermidis, Salmonella para typhi B, Shigella dysenteriae, Klebsiella pneumonia and Escherichia coli), the result showed that the highest activity against Staphylococcus epidermidis and Staphylococcus epidermidis (6mm) where's there medium activity against Salmonella para typhi B and Shigella dysenteriae (5mm) while Klebsiella pneumonia and Escherichia coli showed the lowest activity (4mm). This study shows that the use of G. senegalensis leaves as traditional medicine has a potential effect in treatment of microbial infections with further standardization.