International Journal of Academic Health and Medical Research (IJAHMR)   Year: 2024 | Volume: 8 | Issue: 1 | Page No.: 58-61 Papillary thyroid carcinoma synchronous with high-grade non-Hodgkin's lymphoma: A case report Download PDF Zakaria El Hafi ,,&, Khalil Hjaouj ,, Razika Bencheikh,, Mohamed Anass Benbouzid,, Adelilah Oujilal,, Leila Essakalli,. Abstract: Papillary thyroid carcinoma (PTC) is the most common thyroid carcinoma, accounting for up to 90% of all thyroid malignancies. The association with an hematological malignancy is very rare, representing an incidence of only 7%. We present a case of synchronous papillary thyroid cancer and non-Hodgkin's lymphoma (NHL) and discuss possible dilemmas in diagnosis and treatment. A 60-year-old woman with no medical or radiation history presented with a hard, immobile left supraclavicular swelling. Cervical ultrasound showed the presence of a suspicious-looking supraclavicular adenopathy with two right lobar thyroid nodules classified EU-TIRADS 4. We performed a total thyroidectomy with right central latero-cervical functional left curage and excision of the left supraclavicular adenopathy. Pathological examination revealed papillary thyroid carcinoma synchronous with high-grade non-Hodgkin's lymphoma. After a multidisciplinary consultation, the patient received six courses of chemotherapy before undergoing irratherapy. This article highlights the importance of a multidisciplinary approach in the absence of consensus, given the rarity of this case.