Abstract:
Lymphoma involves malignancy of the lymphatic system which includes the spleen, thymus, bone marrow and lymph nodes. Diffuse large B-cell lymphoma (DLBCL) is an aggressive, rapidly-growing type of non-Hodgkin lymphoma (NHL). In the present case report, a 59-year-old female patient presented with long-term inflammatory pain of the right talus. Magnetic resonance imaging (MRI) was obtained which revealed tissue lesion infiltrating a large part of the talus, with cortical rupture and infiltration of the anterior and posterior soft tissues. Due to concern for malignancy, the patient underwent a computed tomography-guided biopsy of the tissue lesion, and the pathology report confirmed the diagnosis of diffuse large B cell lymphoma (DLBCL). Chest, abdomen and pelvic CT scan showed: bilateral ovarian tumor process, locally advanced on the right, associated with supra- and subdiaphragmatic, right renal, left adrenal and peritoneal lymph node involvement which was consistent with Diffuse Large B-cell lymphoma, Stage IV. The patient underwent 8 cycles of chemotherapy with intrathecal methotrexate. The patient's pain and swelling to the hindfoot had completely resolved and the patient remains in remission.
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