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| Uterine adenofibroma: Case report and literature review
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Z. Hayati, S. Jayi, L. Tahiri Ousrouti, H. Ismaili, Y. Belhaj, Fz. Fdili Alaoui, H. Chaara, Ma. Melhouf
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Abstract:
Uterine adenofibroma is an extremely rare benign tumour that occur, preferentially, in peri and post-menopausal women. It present both clinically and radiologically as benign tumours. In some cases, patients may be asymptomatic with a physical examination may be entirely unremarkable. On ultrasound examination, uterine adenofibromas perfectly simulates an endometrial polyp or a submucosal leiomyoma. As clinical and sonographic features are non-suggestive, the pathological examination remains the gold standard for the diagnosis, revealing a biphasic epithelial and mesenchymal tumour limited to the endometrium or cervical mucosa. Histologically, uterine adenofibroma must be particularly differentiated from adenosarcomas. In this paper, we report a case of an endometrial adenofibroma with a brief literature review. The aim of this work is to remind practitioners of the importance of the anatomopathological study, being the gold standard in the diagnosis of uterine adenofibromas, and to insist on hysterectomy as the treatment of choice for this tumour given its potential for recurrence, invasion and metastasis, as well as the possibility of coexistence with adenosarcoma. However, in young patients wishing to conceive, hysteroscopic lumpectomy may be a therapeutic alternative with a long-term follow-up.
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