Title: Antibacterial Activity of Garlic Ethanolic Extract Against Multi Drug Resistant Bacteria Isolated from Patients with Urinary Tract Infection in Khartoum City, Sudan.
Authors: Hammam Ali Babiker Daffaallah, M.Sc , Sahar Mohammed Seedahmed, Ph.D , Mohammed M.Babeker, Ph.D , Alkhair Abd Almahmoud Idris, Ph.D
Volume: 8
Issue: 8
Pages: 113-123
Publication Date: 2024/08/28
Abstract:
Background Urinary tract infection (UTI) is a major cause of morbidity and may sometimes lead to mortality. and represents a major health threat due to antibiotic resistance and high recurrence rate. The study aimed to testing the antibacterial activity of Allium sativum ethanolic extract against multidrug resistant urinary tract bacterial isolates. Methods This was laboratory-based study included a total of one hundred bacterial isolates were collected from different Hospitals in Khartoum city, Sudan. Results The result showed that amoxicillin had high resistant rates (97.9%) followed by Cephalexin (95.6%) then Cefotaxime (85.5%) , Co-trimoxazole (77.3%) and Ciprofloxacin (72.9%) and finally nitrofurantoin (40.9%). Conclusions Garlic ethanolic extract have a high antibacterial activities against pathogenic bacteria (E.coli, K.pneumoniae , P.aeruginosa and E.faecalis), and standard isolates (E coli ATCC 8729 and S aureus ATCC 6538).