Title: Potentials of Bioactive Compounds from Marine Black Sponges Species in Zanzibar - Tanzania
Authors: Bariki Salum Juma and Khalfan Salim Sule and Khamis Rashid Kheir
Volume: 8
Issue: 8
Pages: 120-124
Publication Date: 2024/08/28
Abstract:
Sponges from the Zanzibar coast, specifically the Jambiani coast, were studied to explore their bioactive compounds, which are crucial for medicinal purposes. Currently, there is a scarcity of data on the bioactive compounds in black sponges from Zanzibar. This study employed extraction methods using dichloromethane, methanol, hexane, ethyl acetate, water, and butanol to isolate bioactive compounds from the black sponges. The extraction methods used included solid-liquid extraction, liquid-liquid extraction, and phytochemical screening. Dichloromethane and methanol were utilized for extracting crude extracts, while water, hexane, ethyl acetate, and butanol were used for separating bioactive compounds.Phytochemical screening analysis was conducted to determine the presence of alkaloids, terpenoids, steroids, phenols, and polyphenols (tannins). The analysis revealed that the sponge extracts contained steroids, alkaloids, and polyphenols (tannins), while phenols were absent in all solvents. These results indicate that black sponges from Zanzibar possess significant bioactive compounds, including terpenoids, steroids, polyphenols (tannins), and alkaloids, which have potential medicinal applications such as anticancer, anti-inflammatory, and antimalarial properties. Further studies are needed to identify bioactive compounds in other sponge species from the Zanzibar Ocean to discover more medicinal compounds.