Title: Assessment of the Correlation between the Prevalence of Anemia and Helicobacter pylori Infection in Western Libya
Authors: Mohamed Daw Said, Azab Elsayed Azab , Ashraf Mohamed Albakoush
Volume: 9
Issue: 2
Pages: 4-11
Publication Date: 2025/02/28
Abstract:
Background: Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic human pathogen and H. pylori infection is strongly related with many gastroduodenal diseases including chronic active gastritis, peptic ulcer diseases, atrophic gastritis, mucosa associated lymphoid tissue lymphoma and non-cardia gastric cancer. Gastric cancer and peptic ulcer together cause more than a million deaths per year in the world and H. pylori infection always is an important health issue. Objectives: The aim of the current study was to find the relationship between Helicobacter pylori infection and the prevalence of anemia. Methodology: The study was carried out over a two month period between August 2022 to October 2022. on consecutive dyspeptic patients who came to the Surman and Sabrtha hospitals during the study period. Two milliliters of the altered blood were later collected in a K3EDTA tube for CBC analysis. A stool antigen test was carried out for H. pylori bacteria. New date and other related data were collected by structured questionnaires. Hematological parameters were determined using the automated blood analyzer Mindray BC-3000 Plus (Shenzhen Mindray Bio-Medical Electronics, China). Results: In the present study, 69 participants were included. Female incidence (48/69) with percentage 69.6% than, male (21/69) whit percentage 30.4%.The majority of participants were in age group above 40 years old with percentage 49.3%, other age group 20-29 and 30-39 were 23.2% and 11.6 % respectively. From total of 69 patients who were on follow-up at Surman, and Sabratha hospitals, a total of 21 (30%) patients were found anemic. However, the normal hemoglobin was found in 48 cases with percentage 70%. The prevalence of anemia concerning gender was 29% for male, wherase for women was 71%.The total number of patients with mild anemia was 15 cases with total percentage ( 71%). On the other hand, 5 cases were found in moderate anemia (24%). And only one case were hade severe anemia with percentage 5%. Conclusion: The prevalence of anemia in this study indicated that it is a moderate public health problem. A higher prevalence of anemia was observed in study participants particularly in female about 70%. Furthermore, the infection with H. pylori strongly related to the age which could be as one of the most important factor for H. pylori infection. The findings of this study should be taken into account for developing intervention-based strategies on identified factors mainly on; prevention and control of H. pylori and intestinal parasitic infection. More criteria may be more important to included in the future studies such as water sources and intestinal parasite anemia among dyspeptic patients. Routine screening of dyspeptic patients for H. pylori infection, hemoglobin estimation of the infected patients and improvement of water sources is advised.