Title: Assessment of Iron Profiles among Patients with Type 2 Diabetes Mellitus Attending Kassala Teaching Hospital, Kassala State, Sudan (2024)
Authors: Rida Abdalnaser Awad, Omer Osman Mohamed, Mohamed Elnaeem Barakat, Hani M. Abdalla, Khalid Abdelsamea Mohamedahmed,
Volume: 9
Issue: 2
Pages: 19-23
Publication Date: 2025/02/28
Abstract:
Background: A chronic metabolic disease that is becoming more common worldwide is type 2 diabetes mellitus (T2DM). This study looks at the connection between T2DM and iron profile markers in patients at Kassala Teaching Hospital, including blood iron, ferritin, total iron-binding capacity (TIBC), and transferrin saturation. Methods: From September to November 2024, a case-control research was carried out in a laboratory. A structured questionnaire was used to collect data from 100 individuals (50 T2DM patients and 50 healthy controls), and SPSS version 22 was used for analysis. Standardized laboratory techniques were used to evaluate serum iron profiles. Results: Serum iron levels were considerably lower in T2DM patients than in controls (P value = 0.000). Serum ferritin (P value = 0.458), TIBC (P value = 0.335), and transferrin saturation (P value = 0.055), however, did not differ significantly. Males showed significantly greater serum iron and transferrin levels than females, according to a gender-based comparison (P value < 0.001). None of the iron profile metrics seemed to be impacted by age. Conclusion: Although age and diabetes have no effect on other iron profile variables, the study shows that T2DM is linked to reduced serum iron levels. Serum iron and transferrin levels were shown to be strongly impacted by gender and the length of the condition.