Title: Osler-Weber-Rendu Disease (Hereditary Hemorrhagic Telangiectasia) and pregnancy: case report and review of the literature
Authors: Mona Aharmouch , Fz Fdili Alaoui , Sofia Jayi , Yassine Belhaj , Hekmat Chaara et Abdelilah Melhouf
Volume: 9
Issue: 2
Pages: 86-90
Publication Date: 2025/02/28
Abstract:
: Osler disease is a dominant genetic vascular disorder that has a prevalence of 1/5000 to 1/8000 and is characterized by recurrent epistaxis, cutaneous telangiectasia, and arteriovenous malformations (AVMs) that affect many organs, including the lungs, gastrointestinal tract, liver and central nervous system. We report the case of a patient transferred to intensive care for decompensation of unrecognized congestive heart failure in per abortum (pregnancy of 15 weeks) whose diagnosis of Osler rendering disease (pulmonary and hepatic AVM) was made on occasion. of carrying out a CT angiogram for suspicion of a pulmonary embolism then benefited from an induction of her pregnancy stopped by cytotec after hemodynamic and respiratory stabilization. Through this observation and the light of a review of the literature, we will discuss screening and management decisions for this rare entity, knowledge of which by practitioners makes it possible to improve the prognosis; given that there is currently no international consensus regarding the medical monitoring of pregnancy in these patients. However, these pregnancies must be considered high risk, due to the potentially fatal events linked to rupture of the arteriovenous malformation