Title: A Rare Convergence: Unexpected In Utero Pulmonary Regrowth in a Fetus Diagnosed with Unilateral Lung Hypoplasia
Authors: (Case Report)
Volume: 9
Issue: 4
Pages: 77-80
Publication Date: 2025/04/28
Abstract:
Background Fetal pulmonary hypoplasia (FPH) is a rare condition associated with underdeveloped lungs, often leading to neonatal respiratory complications. While typically linked to poor outcomes, some cases show potential for lung regeneration in utero. This case report describes a primiparous woman whose fetus exhibited right-sided pulmonary hypoplasia, which resolved by the third trimester. Presentation A 28-year-old woman was diagnosed with right-sided pulmonary hypoplasia at 20 weeks of gestation. Follow-up ultrasound at 24 confirmed the hypoplasia, but by 34 weeks, the right lung had fully developed. The pregnancy progressed without complications, and the neonate was born at 39 weeks without respiratory distress. A postnatal chest X-ray showed no abnormalities. Management Regular ultrasound monitoring was conducted throughout the pregnancy. As there were no additional complications, the pregnancy was managed conservatively with no interventions. Postnatal observation confirmed the neonate's healthy respiratory function, with no need for intensive care. Conclusion This case demonstrates the rare resolution of right-sided fetal pulmonary hypoplasia, suggesting the possibility of fetal lung regeneration. It underscores the importance of close prenatal monitoring and highlights the potential for positive outcomes despite initial concerns. Further studies are needed to understand the mechanisms of fetal lung regeneration.