Title: Survey on antibiotic resistance of Escherichia Coli isolated from patients at Thanh Hoa Provincial Hospital, Vietnam in 2024
Authors: Bach Tuong Vi, Tran Tinh Yen, Nguyen Hoai Nam
Volume: 9
Issue: 7
Pages: 95-102
Publication Date: 2025/07/28
Abstract:
This study evaluates the antibiotic resistance of clinical isolates of E. coli gathered from Thanh Hoa Provincial Hospital during the year 2024. All 886 E. coli strains collected were evaluated for their susceptibilities to 24 antibiotics of different classes using the disc diffusion method, which is in accordance with CLSI 2023 guidelines. The results showed 51.9% of the strains were E. coli, producers of Extended-spectrum beta-lactamase (ESBL). E. coli strains exhibited high resistance to Ciprofloxacin (83.3%), Levofloxacin (75.2%), Ampicillin (98.3%), and Co-trimoxazole (68.5%), while showing high susceptibility to the carbapenem antibiotics Imipenem (97.9%), Meropenem (97.6%), and Amikacin (95.7%). A more detailed analysis by patient characteristics (gender, age, department) and specimen type was performed to provide additional epidemiological context, which complemented the resistance profile mapping. This study emphasizes the need to gather and analyze relevant clinical information to empirically prescribe appropriate antibiotics and formulate strategic treatment plans to mitigate the dissemination of resistant strains.