Title: Investigation Of Phytochemical Constituents And Therapeutic Potentials Of Ziziphus Mauritiana Leaves
Authors: Ahmed Attahiru, Ahmed Musa Ahmed, Bashar Attahiru
Volume: 9
Issue: 8
Pages: 156-159
Publication Date: 2025/08/28
Abstract:
Plants that has medicinal applications represent a rich source of antimicrobial agents. Due to the side effects of antibiotics and the resistance of pathogenic microorganisms against antibiotics, highly much attention paid to plant extracts and biologically chemical active compounds isolated from different plant species. Ziziphus mauritiana is used by local people in Nigeria particularly tin the Northern part of the country as traditional medicine for the treatment of various disorders. This research determined the antibacterial activity from methanolic leaves extract of Ziziphus mauritiana against Staphillococus aureus, Eschericia coli and Bacillus subtillis. The method of extraction used was cold maceration, standard methods were used for the screening of phytochemicals and well diffusion method for the determination of antibacterial activity. The phytochemical result confirms the presence of saponins, tannins, glycosides, alkaloids, phenols, flavonoids, terpenoids and steroids. The antibacterial result indicated that Bacillus subtillis revealed the higher activity ranging from 1.333±0.577 mg/ml to 5.667±0.577 mg/ml. and lowest activity was observed by Eschericia coli 0.000±0.0.00 mg/ml to 3.333±0.577 mg/ml. The antibacterial activity may be due the presence of bioactive compounds in the leaves extract of Ziziphus mauritiana like tannins, alkaloids and terpenoids that have several pharmacological activities.