Title: Fertility in Women with Inflammatory Bowel Disease: A Multidisciplinary Clinical Perspective
Authors: Douha Ziane, Chadia Khalloufi, Houda Moustaide, Saad Benkirane
Volume: 9
Issue: 8
Pages: 13-15
Publication Date: 2025/08/28
Abstract:
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, often affects people during their reproductive years, making fertility a key concern. While treatment advances have improved outcomes, the effects of IBD on fertility remain complex. Fertility can be influenced by active disease, prior pelvic surgery, psychological stress, sexual dysfunction, and certain medications. Women in remission without pelvic surgery usually have normal fertility. However, active inflammation or surgeries in the pelvic area can lower fertility. Emotional stress and the decision to delay or avoid pregnancy also play a role. Some medications, like methotrexate, must be avoided due to their risks in pregnancy, while most biologics are generally considered safe. Supporting fertility in IBD requires a personalized, team-based approach, with open discussions between patients, gastroenterologists, reproductive specialists, and mental health professionals.