Title: Serodetection of Anti-Cytomegalovirus IgG Antibody and Associated Risk Factors Among Healthcare Workers in Wad Medani Pediatric Teaching Hospital, Sudan, (2022)
Authors: Ahd Abdelkreem Yousif Alata, Tanzeel Alamin Almahdi Gorashi ² , Hajir Mohammed Hussien¹, Alaa Faroge Ibrahim ¹, Yosria Mohammed Elsiddig ¹, Fatima Hassan Ahmed ¹
Volume: 10
Issue: 2
Pages: 24-31
Publication Date: 2026/02/28
Abstract:
Background: HCMV has global distribution, particularly among communities with lower socioeconomic status, and mostly infants which represent important vector of HCMV transmission and infection. Thus, exposure to young children in the workplace may predispose to the risk for CMV infection. Objective: This descriptive cross sectional study was conducted to screening 90 healthcare workers at Wad Medani Pediatric Teaching hospital for anti-CMV IgG antibody using ELISA technique. Also to stand on their demographic characteristics and risk factors that may associate with CMV infection. Methods: the study population comprised 90 healthcare workers. Blood samples were separated by centrifugation and Plasma was analyzed for CMV IgG antibodies using ELISA technique. Results: CMV IgG antibodies were present in (75.6%) of the studied subjects were positive and (24.4%) were negative. Statistical analysis of the risk factors showed that there was a significant association between CMV infection and age (P=0.024), job activity (P=0.019), job duration (P=0.001), exposure to children in the house (P=0.025), and wearing gloves during work (P=0.000). Conclusion: in the staff group as a whole the majority of study subjects were positive for anti-CMV IgG antibody. CMV infection was associated mainly with nurses, exposure to children at home, with long job duration as more than 10 years and advanced in age, in addition to greater association with wearing gloves during work.