Title: Metastatic Gestational Ovarian Choriocarcinoma: case report
Authors: M. LAMCHARFI, N. LATRACH, N. DOUZI, M.I. BENDAHHOU, N. MAMOUNI , S.ERRARHAY , C. BOUCHIKHI , A.BANANI
Volume: 10
Issue: 5
Pages: 34-39
Publication Date: 2026/05/28
Abstract:
Gestational ovarian choriocarcinoma is an extremely rare and highly aggressive tumor. Preoperative diagnosis of extrauterine choriocarcinoma is difficult due to its nonspecific clinical presentation and similarity to ectopic pregnancy. We present the case of a 25-year-old woman who was admitted to our emergency department with pelvic pain, vaginal bleeding, and amenorrhea. The patient underwent emergency laparotomy. The discovery of a suspicious ovarian mass led to an adnexectomy. The histopathological results were inconclusive. Then, in view of persistent intermittent bleeding with an increasing hCG level and no evidence on ultrasound, a CT scan revealed secondary pulmonary lesions. A lung biopsy confirmed the diagnosis of gestational choriocarcinoma. It was classified as FIGO stage III and high risk according to the FIGO classification, and the patient underwent multi-agent chemotherapy without major complications and with favorable clinical and biological progression. We conclude that, due to the rarity of this entity, preoperative differentiation between ovarian ectopic pregnancy and ovarian choriocarcinoma is extremely difficult. Diagnosis is based on pathological examination and bHCG level kinetics. Treatment involves chemotherapy adapted to the FIGO stage and risk.