Title: Epidemiological, Clinical, and Therapeutic Profile of Endometrial Cancer: Experience from Hassan II University Hospital in Fez, Morocco
Authors: Boumaaza Sara
Tazi Zineb
Belhaj Yassine
Jayi Sofia
Fdili Alaoui FZ
Hekmat Chaara et MELHOUF Moulay Abdelilah
Volume: 10
Issue: 8
Pages: 98-103
Publication Date: 2026/08/28
Abstract:
Introduction: Endometrial cancer is one of the most common gynecological malignancies and predominantly affects postmenopausal women. The aim of this study was to describe the epidemiological, clinical, paraclinical, histopathological, and therapeutic characteristics of patients managed for endometrial cancer in our department. Materials and Methods: We conducted a retrospective, descriptive, and analytical study including 25 patients managed for endometrial cancer at the Department of Gynecology and Obstetrics II, Hassan II University Hospital, Fez, Morocco, between January 2020 and December 2025. Data were collected from medical records, the hospital electronic database, and multidisciplinary tumor board records.b Results: The mean age was 62 years, and 96% of patients were postmenopausal. Obesity was present in 60% of patients, diabetes mellitus in 52%, and hypertension in 32%. Abnormal uterine bleeding was the main presenting symptom (96%), with a mean delay of six months before seeking medical attention. Hysteroscopy was performed in 80% of patients and pelvic magnetic resonance imaging (MRI) in 92%. Radiological staging showed stage I disease in 64% of patients, stage II in 16%, stage III in 12%, and stage IV in 8%. Twenty-three patients (92%) underwent surgery. Endometrioid adenocarcinoma was the predominant histological type, accounting for 84% of cases. Fifteen patients received radiotherapy and 13 received chemotherapy. Conclusion: In our series, endometrial cancer predominantly affected postmenopausal women, who frequently presented with metabolic risk factors. Abnormal uterine bleeding was the main presenting symptom, and most cancers were diagnosed at an early stage. Surgery was the mainstay of treatment.