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| Analysis of Type II Censored Exponentially Distributed Survivor and Hazard Functions on Chronic Granulomatous Disease Data with Placebo and Interferon Gamma Treatment Methods
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Aqil Azmi Reswara, Lutfiani Azzahra, Mochamad Rasyid Aditya Putra, Toha Saifudin
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Abstract:
Chronic granuloma is a disease associated with primary immunodeficiency that affects the phagocytes of the innate immune system. Several treatment methods have been investigated, including the administration of Placebo and Interferon Gamma. Placebo in the medical world, commonly referred to as a fake drug made similar to the original drug. Interferon as one of the treatment methods that works with the immune system to fight certain diseases. In general, interferons are proteins produced naturally in parts of the body`s immune system that prevent viruses from multiplying. Based on the description above, a study can be conducted to test the survival of GCD patients who are given treatment with Placebo and Interferon Gamma drugs until they recover or die. Based on the results, the proportion of chronic granuloma patients treated with Interferon Gamma (rIFN-g) who survive up to two months is 0.956243, while the proportion of chronic granuloma patients treated with Placebo who survive up to two months is 0.88475. So, it can be concluded that the Interferon Gamma (rIFN-g) treatment method is more effective in healing chronic granuloma patients compared to the Placebo treatment method.
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